What Is Lamin Protein

Lamins have elastic and mechanosensitive properties and can alter gene regulation in a feedback response to mechanical cues.

What is lamin protein.

Laminin has arms that associate with other laminin molecules to form sheets and bind to cells. Laminins are high molecular weight 400 to 900 kda proteins of the extracellular matrix they are a major component of the basal lamina one of the layers of the basement membrane a protein network foundation for most cells and organs the laminins are an important and biologically active part of the basal lamina influencing cell differentiation migration and adhesion. Laminin is defined by the webster medical dictionary as a glycoprotein that is a component of connective tissue basement membrane and that promotes cell adhesion in other words looking at laminin as a kind of glue isn t far from the truth. Laminin is a protein that is part of the extracellular matrix in humans and animals.

Nuclear lamins interact with inner nuclear membrane proteins to form the nuclear lamina on the interior of the nuclear envelope. There are several different laminins. Lamins also known as nuclear lamins are fibrous proteins in type v intermediate filaments providing structural function and transcriptional regulation in the cell nucleus. The lmnagene provides instructions for making several slightly different proteins called lamins.

The lamins are the major architectural proteins of the animal cell nucleus. Lamins line the inside of the nuclear membrane where they provide a platform for the binding of proteins and chromatin and confer mechanical stability. These proteins are made up of a nearly identical sequence of protein building blocks amino acids.